Alternative Drug Names: MK-3475 is now Pembrolizumab (Keytruda brand in the US) Purpose of Trial: This is a phase 2 trial to determine the safety and efficacy of MK-3475 as a single drug in the setting of prior chemotherapy for metastatic IBC. MK-3475 has been FDA...
IBC metastasizes to the brain in about 19% of IBC patients within the first 2 years after diagnosis. Unfortunately the incidence of these metastases is increasing despite more effective systemic therapies that have controlled a subset of other organ metastases for...
Alternative Drug Names: Romidepsin (Istodax brand in the US). Romidepsin is also known as FK228, FR901228, or Depsipeptide; Abraxane is the branded name of Nab-Paclitaxel, a nanoparticle form of Paclitaxel Purpose of Trial: The phase 1 portion of this study is to find...
guest post by Dr Angela Alexander, a TRIUMPH translational postdoctoral fellow at MD Anderson. Her laboratory work focuses on combinatorial treatment approaches to benefit IBC and TNBC patients. Her full bio is at the end of this post and we are so grateful for her...