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Ruxolitinib + chemo upfront TN-IBC

Alternative Drug Names: Ruxolitinib (Jakafi brand in the US) was previously also known as INCB018242. Paclitaxel is often shortened as “taxol”. “AC” is short for adriamycin and cyclophosphamide. Doxorubicin is another name for Adriamycin. Cyclophosphamide may also be...

ACE for metastatic IBC

Alternative Drug Names: Atezolizumab is also known as Tecentriq. Cobimetinib is also known as Cotellic. Eribulin is also called Halavan. Purpose of Trial: This is a trial of a novel combination for chemotherapy-resistant metastatic IBC. The purpose is to determine the...

PLX-3397 + MK-3475 Dual Immunotherapy

Alternative Drug Names: PLX-3397 is also called Pexidartinib. MK-3475 is now Pembrolizumab (Keytruda brand in the US). Purpose of Trial: The purpose of this phase 1/2 study is to establish the safety of the combination of these 2 agents in any solid tumor, and in the...

Dual HER2 + Abraxane

Alternative Drug Names: Nab-Paclitaxel (Abraxane brand in the US), Trastuzumab (Herceptin is the brand in the US and abroad), Pertuzumab (Perjeta brand in the US and abroad) Purpose of Trial: The purpose of this phase 2 study is to evaluate the effectiveness of the 3...

Ruxolitinib + Paclitaxel IBC

Alternative Drug Names: Ruxolitinib (Jakafi brand in the US) was previously also known as INCB018242. Purpose of Trial: The purpose of this phase 1/2 study is 2-fold. In the first part of the study in metastatic breast cancer patients, the goal is to determine a safe...
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