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Ruxolitinib + chemo upfront TN-IBC

Alternative Drug Names: Ruxolitinib (Jakafi brand in the US) was previously also known as INCB018242. Paclitaxel is often shortened as “taxol”. “AC” is short for adriamycin and cyclophosphamide. Doxorubicin is another name for Adriamycin. Cyclophosphamide may also be...

Eribulin-AC HER2- IBC

Alternative Drug Names: Eribulin is also known as Halaven (US brand name) and previously known as B1939 mesylate. “AC” is short for adriamycin and cyclophosphamide. Doxorubicin is another name for Adriamycin. Cyclophosphamide may also be called Cytoxan (brand name)....

ACE for metastatic IBC

Alternative Drug Names: Atezolizumab is also known as Tecentriq. Cobimetinib is also known as Cotellic. Eribulin is also called Halavan. Purpose of Trial: This is a trial of a novel combination for chemotherapy-resistant metastatic IBC. The purpose is to determine the...

Adjuvant Keytuda ER+ stage 3 IBC

Alternative Drug Names: Keytruda is the brand name for Pembrolizumab. It used to be called MK-3475 Purpose of Trial: This trial is testing the concept that activating the immune system in patients who had residual alive cancer at mastectomy will reduce recurrence more...

PLX-3397 + MK-3475 Dual Immunotherapy

Alternative Drug Names: PLX-3397 is also called Pexidartinib. MK-3475 is now Pembrolizumab (Keytruda brand in the US). Purpose of Trial: The purpose of this phase 1/2 study is to establish the safety of the combination of these 2 agents in any solid tumor, and in the...
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