currently enrolling clinical trials for IBC
(Designed for IBC patients or building on IBC research)
Dual HER2 + chemo upfront IBC
Alternative Drug Names: Paclitaxel (Taxol brand in the US and abroad), Trastuzumab (Herceptin is the brand in the US and abroad), Pertuzumab (Perjeta brand in the US and abroad) Purpose of Trial: The purpose of this phase 2 study is to evaluate the effectiveness of...
Nintedanib IBC
Alternative Drug Names: Nintedanib was called BIBF 1120 (Ofev brand in the US) Purpose of Trial: The purpose of this phase 2 study is to evaluate the safety and efficacy of Nintedanib in the setting of metastatic IBC. Nintedanib is FDA approved outside of oncology,...
MK-3475 (Keytruda) IBC
Alternative Drug Names: MK-3475 is now Pembrolizumab (Keytruda brand in the US) Purpose of Trial: This is a phase 2 trial to determine the safety and efficacy of MK-3475 as a single drug in the setting of prior chemotherapy for metastatic IBC. MK-3475 has been FDA...
IBC And Brain Metastases
IBC metastasizes to the brain in about 19% of IBC patients within the first 2 years after diagnosis. Unfortunately the incidence of these metastases is increasing despite more effective systemic therapies that have controlled a subset of other organ metastases for...
Romidepsin & Abraxane IBC
Alternative Drug Names: Romidepsin (Istodax brand in the US). Romidepsin is also known as FK228, FR901228, or Depsipeptide; Abraxane is the branded name of Nab-Paclitaxel, a nanoparticle form of Paclitaxel Purpose of Trial: The phase 1 portion of this study is to find...
Triple Negative Breast Cancer: From Bench to Clinic in 2013
guest post by Dr Angela Alexander, a TRIUMPH translational postdoctoral fellow at MD Anderson. Her laboratory work focuses on combinatorial treatment approaches to benefit IBC and TNBC patients. Her full bio is at the end of this post and we are so grateful for her...