currently enrolling clinical trials for IBC
(Designed for IBC patients or building on IBC research)
Current Clinical IBC Trials Open for New Patient Enrollment
The following list of Current Clinical IBC Trials Open for New Patient Enrollment was shared by MD Anderson in their Illuminating Hope Newsletter, Issue 31, April 2023. Neoadjuvant (newly diagnosed before surgery): None currently – study is on hold for modifications....
Currently Enrolling Clinical Trials for IBC
Currently Enrolling Clinical Trials for IBC (designed for IBC patients or building on IBC research) Neoadjuvant trials: A Randomized Phase II Study of Neoadjuvant Carboplatin/Paclitaxel (CT) Versus Panitumumab/Carboplatin/Paclitaxel (PaCT) Followed by...
Ruxolitinib + chemo upfront TN-IBC
Alternative Drug Names: Ruxolitinib (Jakafi brand in the US) was previously also known as INCB018242. Paclitaxel is often shortened as “taxol”. “AC” is short for adriamycin and cyclophosphamide. Doxorubicin is another name for Adriamycin. Cyclophosphamide may also be...
Eribulin-AC HER2- IBC
Alternative Drug Names: Eribulin is also known as Halaven (US brand name) and previously known as B1939 mesylate. “AC” is short for adriamycin and cyclophosphamide. Doxorubicin is another name for Adriamycin. Cyclophosphamide may also be called Cytoxan (brand name)....
ACE for metastatic IBC
Alternative Drug Names: Atezolizumab is also known as Tecentriq. Cobimetinib is also known as Cotellic. Eribulin is also called Halavan. Purpose of Trial: This is a trial of a novel combination for chemotherapy-resistant metastatic IBC. The purpose is to determine the...
No longer enrolling – Adjuvant Keytuda ER+ stage 3 IBC
Alternative Drug Names: Keytruda is the brand name for Pembrolizumab. It used to be called MK-3475 Purpose of Trial: This trial is testing the concept that activating the immune system in patients who had residual alive cancer at mastectomy will reduce recurrence more...
IBC Skin Metastases Project
Our purpose is to fund research. We met Ria, and her project in Dr. Kenneth van Golen's lab at the University of Delaware has some interesting questions that need to be answered. We have made a commitment to her and Dr. van Golen to support this research. IBC Skin...
PLX-3397 + MK-3475 Dual Immunotherapy
Alternative Drug Names: PLX-3397 is also called Pexidartinib. MK-3475 is now Pembrolizumab (Keytruda brand in the US). Purpose of Trial: The purpose of this phase 1/2 study is to establish the safety of the combination of these 2 agents in any solid tumor, and in the...
Dual HER2 + Abraxane
Alternative Drug Names: Nab-Paclitaxel (Abraxane brand in the US), Trastuzumab (Herceptin is the brand in the US and abroad), Pertuzumab (Perjeta brand in the US and abroad) Purpose of Trial: The purpose of this phase 2 study is to evaluate the effectiveness of the 3...
No Longer enrolling – Ruxolitinib + Paclitaxel IBC
Alternative Drug Names: Ruxolitinib (Jakafi brand in the US) was previously also known as INCB018242. Purpose of Trial: The purpose of this phase 1/2 study is 2-fold. In the first part of the study in metastatic breast cancer patients, the goal is to determine a safe...